Isotope-edited NMR experiments 2D X-edited TOCSY 3D TOCSY-HMQC 3D TOCSY-HSQC 2D X-edited NOESY 3D NOESY-HMQC 3D NOESY-HSQC 3D HMQC-NOESY-HMQC 4D HMQC-NOESY-HMQC Tutorials 2D X-edited 1H Experiments 2D X-edited 1H Experiments 2D X-edited 1H Experiments The protein is usually uniformly labeled with the active isotopes and the ligand is usually unlabeled in protein-ligand complexes. Some examples: Isotope-edited NMR experiments for 13C-labeled protein and unlabeled ligand Isotope-edited NMR experiments for 13C/15N- labeled protein and unlabeled ligand Other links of interest: Several related filters have been described: X-half filter Double-tuned filter elements ( 92JMR199-96 and 92JACS2433 ) New isotope-filtered schem based on double-tuned filter, a hyperbolic secant inversion pulse and a PFG-based z-filter ( 96JB492-8 ). 13C-Filtering using adiabatic 13C inversion pulses ( 97JACS6711 and 97JMR36-127 ). 15N/13C half filters ( 99JB43 ) J-compensated isotope filter ( 99JACS5346 ) Correlation between multidimensional NOE experiments NMR experiments: 86JMR500-70 90QRB39-23 93JB709 92FEBS309-308 98JMR148-131. 13C-w1-filtered 2D experiment 94FEBS87-250 86JACS6162 87QRB51-19 87JMR366-74 91BIO6574 94NAT877 94JMB592-238 2D NOE-difference 1H-13C HSQC experiment ( 01JB195 ) 3D SE X-filtered TOCSY-TOCSY experiment ( 02JB155-24 )
The protein is usually uniformly labeled with the active isotopes and the ligand is usually unlabeled in protein-ligand complexes. Some examples:
NMR experiments:
