Isotope-edited NMR experiments used to study 13C-protein
and 12C ligand complexes:
-
13C(w1)-13C(w2) doubly filtered experiment
which allows to study intramolecular NOEs of
the unlabeled ligand
-
13C(w1)-filtered/13C(w2)-selected experiment which
allows to study intermolecular NOEs between the protein
and the ligand
-
13C(w2)-filtered/13C(w1)-selected experiment which
allows to study intermolecular NOEs between the protein
and the ligand
-
13C(w1)-13C(w2) doubly selected experiment which
allows to study intramolecular NOEs of
the 13C-labeled protein