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Techniques and Instrumentation in IMSERC

IMSERC maintains a comprehensive fleet of instrumentation needed for small molecule characterization and quantitative studies. We can assist with instrument selection or with grant preparation. For details on instrumentation per technique, consult the sub menu items below:

Crystallography

Instrument Funding Source / Acknowledgement
STOE STADI-VARI NU / NSF CHE-1920248
Rigaku oxford diffraction XtaLAB Synergy-DW VHF (DW-Synergy) NU
Rigaku oxford diffraction XtaLAB Synergy-S (Mo-Synergy) NU
Rigaku oxford diffraction XtaLAB Synergy-S (Cu-Synergy) NU
STOE STADI-P NU
STOE STADI-MP NU

Mass Spectrometry

Instrument Funding Source / Acknowledgement
Bruker Impact II q-ToF (HRMS w/ UPLC and nano LC) NU
Bruker AmaZon SL (LCMS ESI Flow Injection) NU
Bruker AmaZon SL (LCMS ESI) NU
Bruker Autoflex III MALDI NU / State of Illinois
Agilent 6210 LC-TOF (ESI, APCI, APPI) State of Illinois
Agilent 5973 GCMS w/ headspace Mirkin Group
Agilent 5973 GCMS Nguyen Group
Waters GC-TOF NSF CHE-0923236
Sciex 6500 Q-Trap (quantitation w/ UPLC and nano LC) S10-OD021786-01

NMR spectroscopy

Instrument Funding Source / Acknowledgement
Agilent 600 MHz DD2 w/ HCN cryoprobe NIH 1S10OD012016-01 / 1S10RR019071-01A1
AVANCE III 600 MHz NU / Int. Institute of Nanotechnology
AVANCE III 500 MHz w/ direct cryoprobe NU
F500 500 MHz DD2 Int. Institute of Nanotechnology
I500 INOVA 500 MHz NSF CHE-9871268
Mercury 400 (Agilent MR400 DD2) Int. Institute of Nanotechnology
Agilent Au 400 (MR400 DD2 Console) NSF CHE-1048773
Solids-400 Mhz (VNMRS console) NSF DMR-0521267

Physical Characterization

Technique Instrument Funding Source / Acknowledgement
Thermal analysis (TGA/DTA/DSC) Jupiter F3 Simultaneous Thermal Analysis NU
Thermal analysis (DSC) TA Instuments DSC Q200 NU
Elemental analysis Xenemetrix ED-XRF NU
Optical AUTOPOL VI Polarimeter NU
Optical Bruker Tensor 37 FTIR (MiD IR / ATR) NU
Optical Delta Nu Raman NU

Below is an example of text that would be used in a typical NSF proposal:

The IMSERC provides a single access point to comprehensive suite of analytical tools to characterize synthetic “small molecules”. The lab operates eight mass spectrometers including an Agilent 6210 time-of-flight LCMS, Waters GC-TOF, Bruker Autoflex III MALDI, two Bruker AmaZon ESI LCMS instrument and two Agilent 6890 GC-MS instruments with quadrupole analyzers. The lab provides small molecule and macromolecular structural characterization capabilities by NMR with a 600 MHz Bruker Avance III, 600 MHz Agilent DDR2 with triple-resonance coldprobe, 500 MHz Avance III with direct coldprobe, two 500 MHz Agilent systems (DDR2 + INOVA), two 400 MHz Agilent DDR2 spectrometers and a 400 MHz Varian instruments solid state spectrometers. Through the NU, UofC, UIC open access initiative, NU users also have rapid access to the 800 and 900 MHz Bruker Avance II spectrometers at UIC which are both equipped with triple-resonance cold probes. IMSERC maintains four single crystal X-ray diffractometers and two powder diffractometers (STOE STADIMP & STADIP) configured for transmission and reflection geometry, and in-situ/operanto experiments. Additionally, the Materials Science J. B. Cohen X-Ray Diffraction facility provides user access to more than ten diffractometers configured for specific experiments. NU researchers also have rapid access to synchotron based X-Ray diffraction at Argonne National Lab’s Advanced Photon Source through the NU managed DND-CAT and LS-CAT beamlines. The IMSERC provides access to FTIR, Raman, UV-Vis and fluorescence spectrometers for optical characterization.