NMR instruments at IMSERC
All the liquid NMR instruments, including A600 and Ag500, are equipped with new SampleXpress auto-samplers.
Au400
Au400 is a 400 MHz Bruker Avance III HD Nanobay system equipped with SampleXpress autosampler. It is used for VT, reaction monitoring and hetero-nuclear NMR experiments.
Features
BBFO Smart probe w/ Z-Gradient
Sensitivity: 1 H=500, 13 C=225, 31 P=150, 19 F=500
VT range: -150 to +150°
Heteronuclear: Yes
Reservation: 1 hour to 48 hours per week
Other Features: Autotune, Automation with Bruker SampleXpress 60-positions autosampler
Funding: National Science Foundation (CHE-1048773)
A600
The Bruker Avance III 600 MHz system has two RF channels. It is used for extended variable temperature and hetero-nuclear NMR experiments in additon to regular proton and carbon ones.
Features
BBFO Smart Probe w/ Z-Gradient
Sensitivity: 1 H=900, 13 C=360, 31 P=250, 19 F=960
VT range: -150° to +150°
Heteronuclear: Yes
Reservation: 1 hour to 48 hours per week
Other Features: autotune, PFG at 55G/cm, SampleXpress
Ag500
The Bruker Avance III 500 MHz system is equipped with DCH CryoProbe. It is fully automated with a SampleXpress autosampler. It is located at B530 of Silverman Hall.
Features
CryoProbe 5mm DCH w/ Z-Gradient
Sensitivity: 1 H=1800, 13 C=1400
VT range: 25°
Heteronuclear: No
Day Time Limit: 10 min per sample, up to 30 min during day time, no limit at night
Other Features: Autotune, Automation with SampleXpress autosampler
HFCN600
This newly upgraded Bruker Neo 600 MHz system w/ QCI-F cryoprobe is primarily used for macro-molecular NMR studies, including protein, DNA, RNA, and carbohydrates. Structure elucidation, natural product, and drug discovery can also benefit significantly from the extremely high sensitivity offered by the cryoprobe. In addtion, it has ultrahigh 19F sensitivity, the best around Chicago area.
Features
QCI (HFCN) Cryo Probe w/ Z-Gradient
Sensitivity: 1 H=5000, 19 F=7000, 13 C=800
VT range: -30° to +70°
Heteronuclear: No
Reservation: 1 hour to 168 hours per week
Other Features: Autotune, PFG at 55G/cm and SampleXpress
X500
The X500 is a Bruker Avance III HD system equipped with a BBO Prodigy probe, which improves the sensitivity by 2-3 times for the heteronuclei while still maintaining excellent sensitivity for proton. It is dedicated for high-throughput application. All the hetero-nuclear NMR experiments can benefit from the high sensitivity and convinience of the SampleXpress auto sampler.
Features
BBO 5mm Prodigy probe w/ Z-Gradient
Sensitivity: 1 H=1200, 13 C=700
VT range: -40° to +80°
Heteronuclear: Yes
Day Time Limit: 20 min per sample, up to 60 min during day time, no limit at night
Other Features: Autotune, SampleXpress autosampler, PFG at 55G/cm
Funding: Northwestern University
Hg400
The Hg400 is a three channell 400 MHz Bruker Avance III HD system equipped with both liquid and solid-state probes. The liquid one is a BBFO Smart probe w/ gradient capable of doing most hetero-nuclear NMR experiments besides regular proton and carbon ones. It also has wide variable temperature capability. We have two solid-state probes on this system. The Bruker 4 mm HX probe is for most of route work. The Phoenix 1.6 mm HFX probe can be used for 19F and 1H with spinning rate up to 40K Hz.
Features
BBFO Smart probe w/ Z-Gradient
Sensitivity: 1 H=500, 13 C=225, 31 P=150, 19 F=500
VT range: -150° to +150°
Heteronuclear: Yes
Reservation: 1 hour to 48 hours per week
Other Features: Autotune
Funding: National Science Foundation (CHE-9871268) and International Institute of Nanotechnology