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For studies of high-molecular weight molecular structures transverse relaxation becomes a limiting factor. Novel techniques that optimize transver relaxation based on cross-correlated relaxation between dipole-dipole interactions and chemical shift anisotropy have become very popular ( 05METH382):
TROSY: Transverse relaxation-optimized spectroscopy CRINEPT: Cross-correlated relaxation-enhanced polarization transfer CRIPT: cross-correlated relaxation-induced polarization transfer