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Nitrogen NMR

PHYSICAL PROPERTIES
 

Isotope
Natural 
Abundance
(%)
Nuclear
Spin
(I)
Magnetogyric
ratio
(107*rad/T*s)
Quadruple 
moment
(1028*Q/m2)
Resonance
frequency
(MHz)
at 11.744T
(500 MHz for 1H)
Relative 
sensitivity
(1H=1.00)
Absolute 
sensitivity
(1H=1.00)
14N
99.632
1
1.9337792
2.044*10-2
36.118
1.01*10-3
1.01*10-3
15N
0.368
1/2
-2.71261804
0
50.664
1.04*10-3
3.85*10-6
 

APPLICATION FIELDS

15N NMR spectroscopy is applied on natural products organic and organometallics compounds, heterocycles, and biomolecules such as peptides and proteins. 15N-labeled compounds are widely used due to its inherent low sensitivity. Better sensitivity is achieved using 14N NMR spectroscopy but undesired broad signals are obtained due to its large quadrupole moment.
NMR REFERENCES
Neat CH3NO2/CD3NO2 is used as an external standard reference (absolute frequency of 10.136767 MHz for 15N and 7.226317 MHz for 14N with respect to 100.00 MHz of TMS). Also see IUPAC recommendations for reporting the NMR chemical shits of all nuclei relative to the 1H resonance of TMS (02JMR323-156).
NMR PARAMETERS
NMR EXPERIMENTS
BIBLIOGRAPHY
 Several interesting reviews have been published: B97BER111, 96ENC3222 , 00ENC1504 , and 86ANG383 .
A complete revision work on modern NMR methodology and application to natural products at natural abundance has been recently reported ( 00JNP543 ).
15N NMR studies on: isoquinoline alkaloids ( 99MRC195 ).