The 2D DQ-NOESY experiment is an hybrid experiment consisting
of consecutive DQ and NOESY building blocks. In the first step, magnetization
is transferred between J-coupled protons via double-quantum coherences
(DQCs) and in the second step, such magnetization is propagated via NOE.
REQUIREMENTS
Easy implementation on AVANCE spectrometers.
VERSIONS
The basic pulse sequence of the DQ-NOESY experiment consists
of a refocused 2D DQ pulse sequence followed by a
NOESY building block
(
85JMR181-61
and
92JMR593-100
).
Modified sequences have been considered:
A related 2D DQ-ROESY experiment
(
92JMR593-100
)
has been proposed by replacing the NOESY mixing time by a ROESY
mixing time.
The 2D DQ-NOESY experiment can be recorded in routine/automation
modes. The most important parameter to consider is the length of the
the DQ and NOESY mixing periods. See 2D DQ and 2D
NOESY experiments for more details.
