Publications

Cason, C. A.; Dolan, K. T.; Sharma, G.; Tao, M.; Kulkarni, R.; Helenowski, I. B.; Doane, B. M.; Avram, M. J.; McDermott, M. M.; Chang, E. B.; Ozaki, C. K.; Ho, K. J., Plasma microbiome-modulated indole- and phenyl-derived metabolites associate with advanced atherosclerosis and postoperative outcomes. J Vasc Surg 2018 , 68 (5), 1552-1562 e7 [10.1016/j.jvs.2017.09.029]
Liu, Y.; Lou, G.; Norton, J. T.; Wang, C.; Kandela, I.; Tang, S.; Shank, N. I.; Gupta, P.; Huang, M.; Avram, M. J.; Green, R.; Mazar, A.; Appella, D.; Chen, Z.; Huang, S., 6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib. FASEB J 2017 , 31 (12), 5453-5465 [10.1096/fj.201700306RR]
Xiao, S.; Coppeta, J. R.; Rogers, H. B.; Isenberg, B. C.; Zhu, J.; Olalekan, S. A.; McKinnon, K. E.; Dokic, D.; Rashedi, A. S.; Haisenleder, D. J.; Malpani, S. S.; Arnold-Murray, C. A.; Chen, K.; Jiang, M.; Bai, L.; Nguyen, C. T.; Zhang, J.; Laronda, M. M.; Hope, T. J.; Maniar, K. P.; Pavone, M. E.; Avram, M. J.; Sefton, E. C.; Getsios, S.; Burdette, J. E.; Kim, J. J.; Borenstein, J. T.; Woodruff, T. K., A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Nat Commun 2017 , 8 , 14584 [10.1038/ncomms14584]
Rivera-Burgos, D.; Sarkar, U.; Lever, A. R.; Avram, M. J.; Coppeta, J. R.; Wishnok, J. S.; Borenstein, J. T.; Tannenbaum, S. R., Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. Drug Metab Dispos 2016 , 44 (2), 220-6 [10.1124/dmd.115.066365]
Kumthekar, P.; Grimm, S. A.; Avram, M. J.; Kaklamani, V.; Helenowski, I.; Rademaker, A.; Cianfrocca, M.; Gradishar, W.; Patel, J.; Mulcahy, M.; McCarthy, K.; Raizer, J. J., Pharmacokinetics and efficacy of pemetrexed in patients with brain or leptomeningeal metastases. J Neurooncol 2013 , 112 (2), 247-55 [10.1007/s11060-013-1055-0]
Ahn, R. W.; Barrett, S. L.; Raja, M. R.; Jozefik, J. K.; Spaho, L.; Chen, H.; Bally, M. B.; Mazar, A. P.; Avram, M. J.; Winter, J. N.; Gordon, L. I.; Shea, L. D.; O'Halloran, T. V.; Woodruff, T. K., Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo. PLoS One 2013 , 8 (3), e58491 [10.1371/journal.pone.0058491]
Simuni, T.; Borushko, E.; Avram, M. J.; Miskevics, S.; Martel, A.; Zadikoff, C.; Videnovic, A.; Weaver, F. M.; Williams, K.; Surmeier, D. J., Tolerability of isradipine in early Parkinson's disease: a pilot dose escalation study. Mov Disord 2010 , 25 (16), 2863-6 [10.1002/mds.23308]
Shanmugam, M.; McBrayer, S. K.; Qian, J.; Raikoff, K.; Avram, M. J.; Singhal, S.; Gandhi, V.; Schumacker, P. T.; Krett, N. L.; Rosen, S. T., Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine. J Biol Chem 2009 , 284 (39), 26816-30 [10.1074/jbc.M109.000646]
Paice, J. A.; Von Roenn, J. H.; Hudgins, J. C.; Luong, L.; Krejcie, T. C.; Avram, M. J., Morphine bioavailability from a topical gel formulation in volunteers. J Pain Symptom Manage 2008 , 35 (3), 314-20 [10.1016/j.jpainsymman.2007.04.016]
Norton, J. T.; Witschi, M. A.; Luong, L.; Kawamura, A.; Ghosh, S.; Stack, M. S.; Sim, E.; Avram, M. J.; Appella, D. H.; Huang, S., Synthesis and anticancer activities of 6-amino amonafide derivatives. Anticancer Drugs 2008 , 19 (1), 23-36 [10.1097/CAD.0b013e3282f00e17]
Wong, C. A.; McCarthy, R. J.; Fitzgerald, P. C.; Raikoff, K.; Avram, M. J., Gastric emptying of water in obese pregnant women at term. Anesth Analg 2007 , 105 (3), 751-5 [10.1213/01.ane.0000278136.98611.d6]
Argiris, A.; Kut, V.; Luong, L.; Avram, M. J., Phase I and pharmacokinetic study of docetaxel, irinotecan, and celecoxib in patients with advanced non-small cell lung cancer. Invest New Drugs 2006 , 24 (3), 203-12 [10.1007/s10637-005-3259-4]
Nitsun, M.; Szokol, J. W.; Saleh, H. J.; Murphy, G. S.; Vender, J. S.; Luong, L.; Raikoff, K.; Avram, M. J., Pharmacokinetics of midazolam, propofol, and fentanyl transfer to human breast milk. Clin Pharmacol Ther 2006 , 79 (6), 549-57 [10.1016/j.clpt.2006.02.010]