Amino Acids: Valine

VALINE VAL, V

CHEMICAL STRUCTURE

CHEMICAL SHIFTS

Standard chemical shifts of random extended chain structures:

¹H^a	¹³C^a	¹⁵N^b
NH: 8.44 HA: 4.18 HB: 2.13 HG: 0.97, 0.94	CO: 174.9 CA: 60.7 CB: 30.8 CG: 19.3, 18.5	N: 121.1

a) from 86BOOK1: b) from 91JMB311-222

More info in:

¹H chemical shifts of amino acids

¹³C chemical shifts of amino acids

Average ¹HA, ¹HN and ¹⁵N chemical shifts in random coil

IDENTIFICATION

Easy spin system identification from:

HA-HB cross-peak in a COSY-DQF experiment.

Typical pattern in a TOCSY experiment.

SECONDARY STRUCTURE

Standard average chemical shift values used in determination of secondary structure by means of the CSI method:
HA: 3.95
CA: 62.2
CO: 176.0
Thus:
          HELIX           B STRAND          COIL
             CA      CO       CA      CO           CA      CO
            65.7    177.5     60.0    174.4      62.3    176.0
More info in: ¹³CA and ¹³CO chemical shifts according to secondary structure.

OBSERVATIONS

RELATED TOPICS

Determination of coupling constants in valine side chains (84BIO5481)