Amino Acids: Tyrosine

TYROSINE TYR, Y

CHEMICAL STRUCTURE

CHEMICAL SHIFTS

Standard chemical shifts of random extended chain structures:

¹H^a	¹³C^a	¹⁵N^b
NH: 8.18 HA: 4.60 HB: 3.13, 2.92 H2,6: 7.15 H3,5: 6.86	CO: 176.0 CA: 57.4 CB: 37.0 C1: 128.0 C2,6: 130.0 C3,5: 117.0 C4: 156.0	N: 122.0

a) from 86BOOK1: b) from 91JMB311-222

More info in:

¹H chemical shifts of amino acids

¹³C chemical shifts of amino acids

Average ¹HA, ¹HN and ¹⁵N chemical shifts in random coil

IDENTIFICATION

Easy spin system identification from:

HA-HB cross-peak in a COSY-DQF experiment.

Typical AMX pattern in a TOCSY experiment.

SECONDARY STRUCTURE

Standard average chemical shift values used in determination of secondary structure by means of the CSI method:
HA: 4.60
CA: 58.0
CO: 175.9
Thus:
          HELIX           B STRAND          COIL
             CA      CO       CA      CO           CA      CO
            60.7    177.2     56.6    174.6      57.5    175.9
More info in: ¹³CA and ¹³CO chemical shifts according to secondary structure.

OBSERVATIONS

RELATED TOPICS