Amino Acids: Cysteine

CYSTEINE CYS, C

CHEMICAL STRUCTURE

CHEMICAL SHIFTS

Standard chemical shifts of random extended chain structures:

¹H^a	¹³C^a	¹⁵N^b
NH: 8.31 HA: 4.69 HB: 3.28, 2.96	CO: 175.7 CA: 57.9 CB: 26.0	N: 118.0

a) from 86BOOK1: b) from 91JMB311-222

More info in:

¹H chemical shifts of amino acids

¹³C chemical shifts of amino acids

Average ¹HA, ¹HN and ¹⁵N chemical shifts in random coil

IDENTIFICATION

Easy spin system identification from:

HA-HB cross-peak in a COSY-DQF experiment.

Typical pattern in a TOCSY experiment.

SECONDARY STRUCTURE

Standard average chemical shift values used in determination of secondary structure by means of the CSI method:
HA: 4.65
CA: 56.8
CO: 174.1
Thus:
          HELIX           B STRAND          COIL
             CA      CO       CA      CO           CA      CO
            60.0    175.1     56.1    172.2      56.0    174.6
More info in: ¹³CA and ¹³CO chemical shifts according to secondary structure.

OBSERVATIONS

RELATED TOPICS