The 2D SECSY (Spin-Echo Correlated SpectroscopY) experiment is a simple version of the 2D J-resolved experiment in which the central 180º 1H pulse has been replaced by a 90º 1H pulse. Presently, this homonuclear correlation experiment is not used.

Easy implementation on any AVANCE spectrometer.

The pulse sequence of the SECSY experiment is a simple echo experiment ( 80JMR321-40 ). After a 90º 1H pulse, transverse magnetization is evolving during the variable mixing time. A 90º 1H pulse is inserted at the middle of this period. Data is acquired as usual. As for the COSY experiment, lonr-range connectivities can also be detected by incorporating a fixed evolution period (d6) into the variable evolution period d0.

The 2D SECSY can be recorded in routine/automation mode.

Tutorials: 2D homonuclear experiments

The SECSY experiment is a homonuclear chemical shift correlation experiment similar to the COSY experiment but the diagonal autocorrelated peaks appear along the F1=0 axis. Since evolution before mixing is only t1/2, all peaks are tilted with a slope of 1/2 and the F2 domain exhibits half of the chemical shift differences and half the splitting due to coupling constants

Related experiments:

2D homonuclear experiments

2D gradient-based homonuclear experiments