1H-1H coupling constants play an important role
to determine
ring conformation. However,
strong coupling effects and overlapping can difficult
the
analysis. The measurement is performed in the usual way. Specific experiments:
One-bond
(
95JACS8645
) and
long-range proton-carbon coupling constants
(
95ACC15
,
95JACS8635
,
97JACS1737
,
97JACS8946
,
99JACS9843
,
99JPCA3783-103
,
00JOC4153
, and
00JPCA9443
) have been also used in conformational studies
Carbon-carbon coupling constants in 13C-labeled compounds.
(
92JACS3499
,
93JACS10863
,
96JMRB69-112
,
97JACS1737
,
97JACS8946
,
98CRS335
,
99JACS9843
,
99JPCA3783-103
,
00JACS396
,
00JOC4153
).
Also see
Conformational studies using
dipolar couplings
J couplings through hydrogen bonds involving OH
(
02OL1831
)