Stereospecific Assignment in Side Chains
Stereospecific assignments of side chain proton resonances improve the precision and accuracy of NMR-determined protein structures (
89JACS3997
,
90BIO1689
,
95BIO5201
). Examples:
Stereospecific assignments of methylene protons (
87JMB611
), including those o proline rings (
95JB123-6
)
Methyl groups of valine and leucine residues (
89JACS3997
,
93FEBS177
,
94JMRB62-104
)
Homonuclear couplings for all side chain angles, particularly for lysine and arginine residues (
95JMRB172-107
,
95JMRB297-106
, and
95JMRB189-108