Non-uniform sampling
In normal conditions, NMR experiments are recorded using Uniform sampling that means that samples are collected at uniform intervals with a fixed number of transients for each sample. Increased resolution of the indirect dimensions of multi-dimensional NMR experiments can be achieved by using
non-uniform sampling
(
04JB1-30
,
05JB141-32
).
Non-uniform sampling can be defined as collecting different number of transients for different sample times. An advantage is that the
tmax can be larger than N(number of points)*DW(dwell time), yielding improved resolution for a given N. Thus, combining Non-uniform sampling with MaxEnt reconstruction, an important gain in acquisition time can be achieved in order to obtain a given resolution.