1H-1H Couplings

Residual 1H-1H dipolar couplings have been reported:
  • A new method called DCOSY (2D Dipolar COrrelation SpectrocopsY) ( 98JACS11210 ) uses a TOCSY sequence to observe long-range proton-proton correlation via dipoalr couplings. Using this approach, through-space interactions at greater distances than those obtained from standard NOESY experiments (up to 7.5 Amstrongs) have been reported. A similar approach has been reported using COSY-DQF ( 98JACS9366 and 98NAT1065 ). Multiple realy peaks can be removed from a CT-COSY experiment. ( 99JACS7712 , 00JB23 and 01JMR242-151).
  • of Methyl groups (DiM sequence) 01JACS1770
  • Other methods have been described in 00JMR435-143
  • Measurement of residual inter- and intraresidue 1HN-1HA dipolar couplings from soft-HNCA-E.COSY ( 99JMR451-139 ) and 3D HNHA ( 00JMR393-142 ) experiments for 13C,15N-labeled proteins.
  • Measurement of magnitude and sign of H,H-dipolar couplings from modified 3D JHH-NOESY ( 00JACS3975 ) and 3D JHH-TOCSY ( 00JB343 ) experiments.
  • Homonuclear TOCSY transfer through residual couplings
  • Using MOCCA ( 01JMR58-149 ).
  • Using MOCCA-SIAM (02JB211-23).
  • Determination the relative sign and size (04JMR49-169)
  • Clean TOCSY through RDCs (04JMR238-168). COmparison of several mixing sequences.
  • Direct structure refinement ( 00JMR393-142 )
  • From a SS-HMQC2 experiment ( 02JACS9672 )
  • Measurement of J(HH)(and D(HH)) and J(CH)(and J(DH)) in methyl groups from related 2D HSQC experiments ( 02JACS14616 and 05JMR36-172 ).
  • From a 2D selective J-resolved experiment ( 04JMR85-172 )
  • Using J-modulated 1D COSY experiments ( 04JACS13100 )
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