Easy implementation on AVANCE spectrometers equipped with pulsed field gradients, selective excitation using shaped pulses and inverse probehead.

Selective 1D HCP using doubly-selective CW irradiation:

Selective 1D HCP using a selective carbon pulse and non-selective HCP:

Spin-edited HCP version:

The selective ge-1D HCP experiment can be run with minor changes from a predefined parameter set.

In a selective 1D HMQC spectrum, only protons directly attached to an specific carbon will be present. The use of gradients allows to obtain a clean, artefact-free spectrum in a short time in which perfect suppression of undesired 1H-12C magnetization is achieved with a single two-step phase cycle.

The selective ge-1D HCP experiment can be used as a starting building block in more sophisticated pseudo-3D experiments.