NMR Periodic Table: Cadmium NMR

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Cadmium NMR

PHYSICAL PROPERTIES

Isotope	Natural Abundance (%)	Nuclear Spin (I)	Magnetogyric ratio *(10⁷rad/Ts)*	Quadruple moment *(10²⁸Q/m²)**	Resonance frequency (MHz) at 11.744T (500 MHz for protons)	Relative sensitivity (¹H=1.00)	Absolute sensitivity (¹H=1.00)
¹¹¹Cd	12.80	1/2	-5.6983131	0	106.027	9.54*10^-3	1.21*10^-3
¹¹³Cd	12.22	1/2	-5.9609155	0	110.914	1.09*10^-2	1.33*10^-3

APPLICATION FIELDS

¹¹³Cd NMR spectroscopy is applied on inorganic and organometallic cadmium-containing compounds. Cadmium is also used as a probe for structural and mechanistic studies of proteins containing Cd or those in which Zn is substitued by Cd at their active centres (96ENC1085). Solid state studies has also been reported.

NMR REFERENCES

Typical standard samples are external 0.1M Cd(ClO₄)₂ in aqueous solution or neat (CH₃)₂Cd (641ppm). The absolute frequency of neat (CH₃)₂Cd is 22.193175 MHz with respect to 100.00 MHz of the TMS signal. Also see IUPAC recommendations for reporting the NMR chemical shits of all nuclei relative to the ¹H resonance of TMS (02JMR323-156).

NMR PARAMETERS

Some interesting features of the Cd nucleus are:

¹¹³Cd chemical shift range: +700/-125 ppm. Identical chemical shifts are found for the ¹¹¹Cd isotope.

Short T₁ values.

NMR EXPERIMENTS

In Cadmium-containing compounds the following experiments can be helpful:

¹H-decoupled vs ¹H-coupled ¹¹³Cd spectrum.

2D ¹H-¹¹³Cd HMQC experiment ( 85JACS1775 , 85JMR579-61 , 88JMB251 , 00MRC452 ).

2D ¹¹³Cd-¹¹³Cd COSY experiment ( 85ICAL71 , 85JACS6847 ).

2D ¹³C-¹¹¹Cd and ¹³C-¹¹³Cd HMQC experiment using carbon detection.

BIBLIOGRAPHY

Interesting review: B91PRE264.
The Transition Metals NMR: B79HAR195.
113Cd NMR in proteins ( 96ENC1085 )
93IC4632-32
92JMR581-100
92JACS8590

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