Determination of the molecular aggregation state of nucleic acids (
97JB255-10
)
CGCGAATTCGCG (D12, 12-pair DNA duplex): 1.23*10
-6
cm
2
/s
GCCCTTTTTATAGC (D14, 14-pair DNA duplex): 1.18*10
-6
cm
2
/s
CGCGAATTCGCGCGCGAATTCGCG (D24, 24-pair DNA duplex): 0.95*10
-6
cm
2
/s
CGACCGGAACGUCC ((R14, 14-pair RNA): 1.41*10
-6
cm
2
/s (monomeric)
CGACCGGAACGUCC ((R14, 14-pair RNA): 0.92*10
-6
cm
2
/s (duplex)
In general, D(duplex):D(monomer) = 0.65
Study of the conformational states of single-straned DNA dodecanucleotides (
97JB383-10
).
Standards:
8-mer d(CG)
4
: 1.65*10
-6
cm
2
/s
12-mer d(CG)
6
): 1.46*10
-6
cm
2
/s
20-mer d(CGTACTGTTAACTAGTACG) : 1.21*10
-6
cm
2
/s
12-mer d1s: 1.36*10
-6
cm
2
/s (monomeric)
DNA-DNA DII: 0.99*10
-6
cm
2
/s (duplex)
Study of the flexibility and curvature of DNAs as a function of the temperature (
00BIO153
)