The main advantages of using PFG in high-resolution NMR experiments include:

• Coherence selection and frequency-discrimination in the indirect dimension (F₁) can achieved with a single scan per t₁ increment.
• A reduction in the number of required phase cycle steps for the suppresion of undesired artefacts.
• An important decrease in the total acquisition times for sufficiently concentrated samples.
• The obtention of higher quality spectra with an important reduction in t₁ noise.
• An efficient suppression of undesired signals such as, for instance, the intense solvent signal in H₂O solution and the ¹H-¹²C (¹H-¹⁴N) magnetization in proton-detected heteronuclear experiments at natural abundance. In these inverse experiments, the starting BIRD cluster or spin-lock pulses are not longer needed and, therefore, there is no need to optimize the null-point delay.
• A much easier data processing and, therefore, more accurate spectral analysis.
• A decrease of dynamic-range limitations.