Operation modes in LC-NMR:

On-flow HPLC-NMR (continuous flow): The sample is measured without stopping the flow. The result is typically displayed as a 2D time-frequency plot representing 1D spectra vs retention time. The method is suitable for a rapid screening of the major components.

LC-NMR under statid conditions:

Stopped-flow HPLC-NMR

Loop-storage procedure

Other hyphenated techniques

LC-SPE-NMR