Accordion spectroscopy
The principles of ACCORDION spectroscopy were reported in the original work of Ernst and Bodenhausen (
82JACS1304
) Applications:
It can be used to overcome the necessity of acquiring separate experiments by optimizing for all couplings in a single experiment. Examples are:
Accordion-optimized HMQC (
00MRC452
) and accordion-optimized HSQC (
01MRC1
).
Variants of
gradient-enhanced 2D HMBC experiment
: the accordion-optimized HMBC or ACCORD-HMBC (
98MRCS44
,
99MRC517
), CIGAR-HMBC (
00MRC143
), IMPEACH-MBC (
99JMR274-140
,
00JMR232-146
),J-IMPEACH-MBC (
01MRC127
). Application on 15N (
00MRC251
)
Measurement of nJCH from HECADE (
97JMR383-124
) and EXSIDE
Measurement of 1JNH (
96JMRB269-112
) .
Measurement of nJ(PH) (
96JMRB46-113
).
Measurement of diffusion coefficients (
98JMR166-131
)
Measurement of relaxation rates in labeled biomolecules (
98JMR25-132
)
Frequecy-domain analysis of relaxation accordion data (
01MRC447
)
Accordion spectroscopy